remove the negative battery cable and let it sit, in the meantime clean the cylinder lock and inspect for damage, then reinstall your lock cylinder and then reconnect your negative battery cable, insert the key turning it to the on position, that should remedy it, and yes any time you do ignition switch, you should remove the negative terminal, the sensor is in the cylinder and measures resistance, so removing it with power to the system trips the anti theft,
as for sticky ignition my 90 ranger did the same thing, i pulled the lock cylinder and cleaned it out really well with some brake cleaner to get all the gunk out and it works normally,
if you have any issues after you put the cylinder back in, you should be able to disarm it by using the key fob (if you have one) to lock and unlock the doors or hitting the panic button, if no remote entry, you should be able to lock and unlock any door with the key then turn the key to the on or acc position, and that should disarm the anti theft