In my 4.0 4x4 4.10 geared Ranger I hardly noticed the difference between
home ~1100ft and Casper, WY @5000ft, but then again I only run 235's
on my truck, it DOES have Borla headers on it and it was the first week I really drove the truck after installing the 4.0 after being used to a 2.9 for ~500k miles....
So my judgement may have been skewed....
And the additional 1000ft to my brothers "ranch" in BarrNun was insignificant.
Climbing over pass into the Casper range at 8500ft, you started to notice
the elevation, but... to be honest what I noticed most was the loss of
cooling system efficiency as demonstrated by a climbing temp guage.
On a slight "quibble" with Will's statment.
On a turbocharged engine there can still be a difference, the magnitude
of the difference depending on how agressively tuned the engine is at sea level.
If you are tuned to be using "most" of the turbochager at low altitude you
can get out of the efficiency island when you try to run much boost at
elevation, so while there will be less of a performance loss, there will be some.
OTOH if your turbo is capable (flow volume) of making 20psi at sea level
(regardless if the engine detonates at that pressure or not)
and it's tuned to run 12-14psi without detonation you are unlikely
to notice a loss of performance at any elevation in north america
where you can find a paved road,
infact while the engine will be making the same power at elevation
it'll be fighting less wind drag in the thinner air and may actually
see an increase in performance!
Yes, it takes the same energy to increase your gravitational potential energy
(climb a grade) but you've reduced the wind drag by an ammount proportional to
the power loss.
BTW, I've driven a Geo Prizm, they are pretty wheezy at low altitude

Hell, I thought the '98 Escort my brother bought my mom was an improvement
over the geo...
Then again, I'm more used to an older Saab 900 Turbo...
I really need to get my Saab back together and drive to see
my brother... that car should be a real hoot at altitude.
AD