No. The SOHC engine is already a higher compression motor with somewhere around 9.7:1 ratio. A real good tune and cool air charge will accept single digit boost pressures, but any more and you'll be barking up the detonation tree. Drop down to 8.8-9.0:1 and you'll be able to run a lot more pressure (this isn't an N/A motor). Also, the cylinder head deck design sucks for high cylinder pressure. Each cylinder has 8 coolant passages and 4 stud holes. That is 12 holes around each cylinder! Even the best gaskets are going to have a hard time not separating.
I would check out the 05-10 mustang V6 guys who have work done to their engines. The rotating assembly from the factory is balanced and is actually a decent system. The crankshaft is stout and the connecting rods have been pushed safely by guys running 400hp at the flywheel. Any big name piston manufacturer should have low comp forged pistons for you. The question is, will the rest of the drivetrain and truck handle it? The 5R55E and M5OD-R1HD both will not hold the power of a 350-400hp torque happy turbo motor. The 28 spline 8.8 axles have been known to throw their guts out the back at 400hp with enough tire (unless you stuff your rear end with aftermarket parts). When I did my V8 swap I was right around 400 at the flywheel and the frame did NOT like that. If it wasn't for an unfortunate accident, I would have ended up boxing the frame and running a roll cage along with bracing (had big plans for drivetrain lol).
Moral of the story, a conservative tune on 6-7 intercooled psi will be about the limits of drivetrain and rotating assembly. Need more? If you have a 2wd then i encourage you to look toward the 4.0L mustang guys.