Oxygen Sensor Issue F250 6.8L v10

[89Twincharge]

Oh yeah and check the fuses for the fuel injectors and the grounds associated with them

 

[Bionicjoe]

B1s2 doesn't control fuel it is merely there to check condition of catalytic converter and will not cause misfires. Bending a fragile plastic tube on the other hand does create cracks especially in the flex areas. Since your cats were stolen b1s2 probraby had a cel since then... Your misfire didn't start then did it? Don't just chase the check engine light. It's merely an aid in finding some problems that are actually detectable by the ecu.

Cat was gone when I bought the truck. It ran perfectly fine since changing the plugs 6 months ago.
However you may be correct that the sensor hasn't been working since before I had the truck.
To be honest I'm not sure how I could've broken a wire now that I know how the harness runs. A crack in the plastic seems likely. There is a support in the back of the engine, up underneath the cowl/firewall that has broken. Could be the issue.