Yes, no unnecessary wiring in a Ranger engine.
Maybe you want to switch to a carb and distributor engine, with just a temp sender and oil pressure sender.
Could put in a V8 as well and have a pretty much wire free environment under the hood.
Change the fuel tank setup for mechanical fuel pump and your all set.
Cutting sensor wires as you described on the Neon would be, well, dumb, lol.
If the sensor wasn't needed, and engine ran fine without it then a short in that circuit wouldn't bother anything so why bother cutting it out?
What would be the benefit?
And I can't think of that many sensors in any case.
TPS, tells computer when and where your foot is on the gas pedal
MAF, tells the computer how much air is coming in and at what temperature so it can set proper fuel/air mix
ECT, electronic choke for fuel injected engines, computer runs engine rich with higher idle until engine warms up
O2 x 3, tells computer if it's MAF fuel/air mix is ok, fine tunes lean/rich, 3rd O2 tells computer if Cat is working
CPS, used by computer to time fuel injectors and sometimes rpm
CKP, tells computer the crank shaft is moving so start ignition/spark, also used to detect misfires and rpm
Not really sensors
EGR, opens to allow exhaust gas into intake, this makes engine run cooler under load(no pinging) and lowers emissions
IAC, controlled vacuum leak used by computer to set idle levels
Dash board Temp gauge sender
Oil pressure sender/switch
Oil level sender/switch(on oil pan) if so equipped
Non-engine sensors
EVAP, tells computer if fuel system is sealed, prevents gas fumes from leaking out of the fuel system.
But all sensors are used at one time or another, some are not 24/7.
Computer controlled engines are more efficient, that's why they are the way they are, carbs and distributors wasted fuel.
If MPG is not on your must have list then I would look at an engine swap, without computer control
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