I never had outward physical signs like you had originally mentioned, but i go through bouts of similar things and basically it can all be summed up as stress. sleeplessness, anger, anxiety were my outward signs i suppose, but anytime i get stressed i feel one or all of those. with the help of someone very important to me i just completed over 2 years of regular therapy with a shrink. stress will never go away, the world we live in today is far far to complicated, however the way a person deals and responds is controllable. id say it was less an issue of yes or no your going nuts with 2 years of therapy, but more a process of learning what makes me tick. i had some traumatic times early in life and it put me in a position to not deal with reality too well, but i never knew the difference! i was always pissed at something never knowing what it was but always feeling restless, sleepless, anxious, angry...pile on starting a career, buying a house, trying to just remain stable and it got way over my head really fast.
between the therapy, eating a better diet, exercise, and as mentioned i keep journals or write lists, i've managed to feel much more in control lately and not lay there staring into the dark for hours and hours wondering what the in the world is wrong. multivitamins, tea, better diet, and knowing why i react the way i do to things has made me much more capable of controlling the reactions and in the long run has reduced stress, reduced all the other things.
i firmly believe in something like herbal therapy and making sure you have a balanced diet. seems like too many doctors just 'plug' you into something and expect a result when it could just be your not getting enough vitamin C or something dumb like that.
sorry for the ramble- i just feel your pain. for nearly 20 years i dealt with a monkey on my back that i never knew was there that caused a lot of sleepless nights.