i always go through a vehicle & change everything, got a S10 blazer for the wife (free from dad) it had 180,000 on it, both diferentials were low & the axle fluid really smelled bad too! after refilling with fresh i soon discovered both front & rear axles needed axleshaft seals....and if you ride in the back theres a definate bearing noise in the rear axle, got a spare axle out to the farm if i ever need it, so not really worring about it. brake fluid? usually at some point in time i need a caliper, wheel cylinder or a brake line goes bad. when i bleed the system i run enough through that its all fresh fluid by the time im done. usually dont worry about the clutch fluid, but due to some recent issues, ive got all new clutch hydraulics and the fluid of course is now new as well. powersteering fluid i dont mess with unless it looks really bad, had a line go about 5-6 years ago, so its got new fluid as of the line replacement. i have heard of a inline p/s fluid filter. all in all, any new to you vehicle with over 100,000 miles should get a real going-through, someone earlier said "you can never over maintain a vehicle" i second that!