i understand your intention.
your premise is off a bit though.....55 wasnt the speed limit in 94. but your premise is right, more right then many care to apply.
your best bet is to dyno the vehicle and find the torque curve...gear it to that with 75 mph the cruise base.
the balance of it all is tough to nail down. i myself play this game all the time..
it cost me 80 bux to drive my 8000 pound(7200 # unloaded) psd van 1600 miles...it averaged 20.8 mpg. on straight diesel it gets 22-23 mpg @ 62-65 mph...thats one way to work site...
my ranger is on its last legs, its equipped with a 6.5 diesel. it needs injectors and a pump as they are just worn out...still pulls 17 mpg.
when it was sub 300k 20 plus mpg was easy under 60 mph....410 gears 33-35 in tires.
but i couldnt drive it comfortably above 65 mph....mpg went 20 plus to 16 hiway above 60 sometimes lower.
put on 37 in tires and i can comfortably cruise 75 mph.....yaaaay. but uhhhh...mpg loss. no 20 mpg.
likely a turbo and fresh fuel system tuneup will put it over 20 mpg at 68-72 mph.
planning on finding out here shortly.
operating an engine out of its power band is a sure way to 14 mpg if its mechanically sound.....
if you have buddies close that can let you test larger and smaller tires, it will be the easiest cheapest way to nail down your suspicions with reality.
i have bought tires on wheels from the junkyard and done that to dial in my e350
355 gears and skinny 32 in tires with the e4od gets it done pretty good.
20.8 mpg on a 30/70 mix of fuel and used oil with 8 k of vehicle/load just perplexes me.
my ranger new never did that
14-15 mpg with a 2wd stock power mini truck would land me into a swap situation....either swap to a better vehicle or better powertrain.
start with smaller tires and make damn sure your way to track miles is accurate....maybe you are really getting 18 mpg and your speedo is just off.

you have me interested in what you can tune to.