Does higher octane fuel ping less or not at all?
What's the MPG like, lower, higher, or no noticeable change?
What's the engine temp like, does it go up higher at highway speeds or lower?
I assume no CEL(check engine light) now and no codes, any codes in the past?
The Bluetooth OBD2 plugins are not to expensive, they can display live data on smartphone or tablet while driving.
You could check that computer is opening EGR valve and also check Fuel Trims and O2 sensor voltage to see if it is getting Lean at higher demand, higher speed.
Also spark advance, computer may not be advancing spark enough for engine load.
Has fuel filter been changed in the last 5 years?
If not flow could be dropping a bit under high demand.