I've already stated that I think the Ecoboost would be a really cool swap, but the OP asked if "things will bolt up?" Everything at this point about fitment, fuel economy in a ranger, how much cutting, wiring, or fabbing is required to fit in a ranger is all speculation. The cost of the drivetrain that you find at some point in the future is speculation as well. The fact is, we don't know.
What we do know, is a 5.0 swap, or 2.3T swap is about as close to bolt in as engine swaps get in a Ranger. There is plenty of info about each swap on this forum and many others. Each swap is capable of generating numbers similar to, or in some cases better than the ecoboost. And when the OP encounters a problem with his swap, he will actually have places like TRS where he can come for help, instead of people just guessing.
Again, I'd like to see the EB swap attempted, but I think we can all agree that being the guinea pig for a completely unproven swap would require skills, knowledge, and preferably experience. When the OP asks if "things will bolt up", it makes me think that throwing them into something as complex as an Ecoboost swap on their own is probably not wise. You have to crawl before you can walk.
Just for my own curiosity, anybody know how much an Ecoboost v6 weighs? What about that giant RWD trans?