Rust:
Look closely for rust in the rear cab corners, bottoms of doors, drivers floor board, the front of the fuel tank where the plastic skid plate is, above the plastic liner in the beds wheelwells (Rusts heavily in the bed side above the wheel wells), the rocker panel behind the rear wheel near the rear bumper, the lower corners of the radiator support under the radiator, under the rubber window sills, in the corner of the floor and the rear cab wall, the bottom of the tailgate, and the rear spring shackles.
A couple more spots that are prone to rusting are the roof corners, under the gas pedal, the seam where the cab floor meets the firewall sheet metal, and right smack dab in the middle of the doors, look for rust bulging/bubbling. Check the floor for wetness on either side of cab floors, and down beside the fusebox/kick panels/computer for water dripping, signs of a poorly done windshield, or one that leaked a bit and was sealed up with silicone.