No, you can't/shouldn't do that swap
2000 has a 4.0l OHV engine, which is "blown"
2001 has a 4.0l SOHC engine, different engine
You need the 2000 computer to run the automatic, 2000 computer can not run the 4.0l SOHC engine, so no go
You could buy a 2001 4.0l SOHC automatic computer..................................
2000 Automatic is a 5R55E but..................the 2001 5R55E had 2 added sensors that the 2001 automatic computer needs
So can't use the 2000 5R55E trans have to buy a 2001-2011 4.0l automatic
2000 4WD Ranger uses the GEM Module as 4x4 controller and SPEED calibrator
2001 4WD Ranger had a separate stand alone 4x4 controller and computer does the SPEED
But have to have the 2001 5R55E automatic for that
2001-2003 would be fine to do the swap
1998-2000 would be fine
2000/2001 not so much, just too many differences
Look for a blown up 2001-2003 4x4 4.0l automatic Ranger
Its still hard work to re-enforce the frame up front and mount the front axle but doable